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Product Identification
Synonyms: 1,3,7-trimethylxanthine
CAS No.: 58-08-2 Molecular
Weight: 194.19
Chemical Formula: C8H10N4O2
HS Codes: 29 39 30 00
Composition/Information on Ingredients
Ingredient : Caffeine
CAS No :
58-08-2
Percent : 100%
Hazardous : YES
Hazards Identification
Emergency Overview
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO
SKIN, EYES AND RESPIRATORY TRACT.POSSIBLE BIRTH DEFECT HAZARD.
MAY CAUSE BIRTH DEFECTS BASED ON ANIMAL DATA.
Health Rating: 2 - Moderate
Flammability Rating : 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip : GOGGLES; LAB COAT
Storage Color Code : Orange (General Storage)
POTENTIAL HEALTH EFFECTS
Inhalation:
Inhalation of dust may irritate the mucous membranes and
respiratory tract. High concentrations may produce effects
paralleling ingestion.
Ingestion:
Toxic. The adult mean lethal dose is approximately 10 gm. Large
doses may produce palpitation, excitement, insomnia, dizziness,
headache and vomiting.
Skin Contact:
Causes irritation to skin. Symptoms include redness, itching,
and pain.
Eye Contact:
Causes irritation, redness, and pain.
Chronic Exposure:
Excessive use of caffeine may lead to digestive disturbances,
constipation, palpitations, shortness of breath and depressed
mental states.Possible teratogen. May cause congenital
malformation in the fetus.
Aggravation of Pre-existing Conditions:
No information found.
First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical
attention.
Ingestion:
Induce vomiting immediately as directed by medical personnel.
Never give anything by mouth to an unconscious person. Get
medical attention.
Skin Contact:
Immediately flush skin with plenty of water for at least 15
minutes. Remove contaminated clothing and shoes. Get medical
attention. Wash clothing before reuse. Thoroughly clean shoes
before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15
minutes, lifting lower and upper eyelids occasionally. Get
medical attention immediately.
Fire Fighting Measures
Fire:
As with most organic solids, fire is possible at elevated
temperatures or by contact with an ignition source.
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in
the presence of an ignition source is a potential dust explosion
hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full face piece operated
in the pressure demand or other positive pressure mode
Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill.
Wear appropriate personal protective equipment as specified in
Section 8. Spills: Clean up spills in a manner that does not
disperse dust into the air. Use non-sparking tools and
equipment. Reduce airborne dust and prevent scattering by
moistening with water. Pick up spill for recovery or disposal
and place in a closed container.
Handling and Storage
Keep in a tightly closed container, stored in a cool, dry,
ventilated area. Protect against physical damage. Containers of
this material may be hazardous when empty since they retain
product residues (dust, solids); observe all warnings and
precautions listed for the product
Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep
employee exposures as low as possible. Local exhaust ventilation
is generally preferred because it can control the emissions of
the contaminant at its source, preventing dispersion of it into
the general work area. Please refer to the ACGIH document,
Industrial Ventilation, A Manual of Recommended Practices, most
recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is
apparent, a half-face dust/mist respirator may be worn. For
emergencies or instances where the exposure levels are not
known, use a full-face positive-pressure, air-supplied
respirator. WARNING: Air-purifying respirators do not protect
workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves,
lab coat, apron or coveralls, as appropriate, to prevent skin
contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where
dusting or splashing of solutions is possible. Maintain eye wash
fountain and quick-drench facilities in work area.
Physical and Chemical Properties
| Appearance |
White powder. |
| Odor |
Odorless. |
| Solubility |
1 gm in 46 mls water. |
| Specific Gravity |
1.23 |
| pH |
5.5-6.5 (1% aqueous solution) |
| % Volatiles by volume @ 21C (70F) |
0 |
| Boiling Point |
178°C (sublimes) |
| Melting Point |
235°C - 237.5°C (460F) |
| Vapor Density (Air=1)
|
No information found. |
| Vapor Pressure (mm Hg) |
No information found. |
| Evaporation Rate (BuAc=1) |
No information found. |
Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, nitrogen
oxides.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Incompatible with strong oxidizers, iodine silver salts,
tannins, and with strong solutions of caustic alkalis.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
Toxicological Information
Toxicological Data:
Oral rat LD50: 192 mg/kg. Investigated as a tumorigen, mutagen,
reproductive effector.
Reproductive Toxicity:
May cause teratogenic effects.
---------------\ Cancer Lists \--------------------
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Ingredient |
Known |
Anticipated |
IARC Category |
|
Caffeine (58-08-2) |
No |
No |
3 |
Ecological Information
Environmental Fate:
When released into the soil, this material may biodegrade to a
moderate extent. When released into water, this material may
biodegrade to a moderate extent. This material is not expected
to significantly bioaccumulate.
Environmental Toxicity:
No information found
Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
managed in an appropriate and approved waste disposal facility.
Processing, use or contamination of this product may change the
waste management options. State and local disposal regulations
may differ from federal disposal regulations. Dispose of
container and unused contents in accordance with federal, state
and local requirements.
Transport Information
D.O.T.
Shipping Name : TOXIC SOLID, ORGANIC, N.O.S.(CAFFEINE)
Hazard Classification : ORM - E
Identification No. : NA 9188
Other Shipping Regulations : None ; no limit with passenger or
cargo aircraft
Exception : None .
Specific Requirement : 173.1300 in Hazardous Material Regulation
of the Department of Transportation ( 1981 )
Regulatory Information
Australian Hazchem Code : No information found
Poison Schedule : No information found
WHMIS : This MSDS has been prepared according to the hazard
criteria of the Controlled Products Regulations (CPR) and the
MSDS contains all of the information required by the CPR.
Product Use
Central stimulant , veterinary-cardiac and respiratory stimulant
and diuretic .
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